Golden Retriever Genetic Pack

Tests included in this pack (6)

• Canine Progressive Retinal Atrophy (prcd-PRA)
• GR-PRA1 (Golden Retriever)
• GR-PRA2 (Golden Retriever)
• Muscular Dystrophy (MD) Golden retriever
• Ichthyosis type 1 and 2 (Golden retriever)
• Neuronal Ceroid Lipofuscinosis 5 (NCL5) - Golden Retriever

Each test includes the complete analysis and detailed report. Click on the test to see its details.

Diseases included in this pack

Canine Progressive Retinal Atrophy (prcd-PRA) (Autosomal recessive)

Inherited degeneration of the retinal photoreceptors. It begins by affecting the rods (night blindness, difficulty in low light) and progresses toward total vision loss in the medium to long term. It is the most common form of progressive retinal atrophy in dogs and is painless, so it is usually detected late, when…

GR-PRA1 (Golden Retriever) (Autosomal recessive)

Late-onset form of progressive retinal atrophy (PRA) of the Golden Retriever, the canine equivalent of human retinitis pigmentosa. It causes photoreceptor degeneration with loss of night vision first and complete blindness afterwards. It is inherited in an autosomal recessive manner and is associated with a frameshi…

GR-PRA2 (Golden Retriever) (Autosomal recessive)

Second specific form of Golden Retriever progressive retinal atrophy, of late onset and recessive, caused by a mutation in the TTC8 (BBS8) gene. TTC8 is part of the BBSome complex involved in ciliary membrane biogenesis and photoreceptor function; its loss produces retinal degeneration progressing to blindness. Some…

Muscular Dystrophy (MD) Golden Retriever (X-linked recessive. Hemizygous males are affected; heterozygous females are usually asymptomatic carriers.)

Golden Retriever muscular dystrophy (GRMD) is an X-linked recessive inherited disease that causes progressive muscle degeneration, homologous to human Duchenne muscular dystrophy. It is characterised by progressive muscle weakness and atrophy with replacement of muscle by fatty and fibrous tissue, affecting skeletal…

Ichthyosis Types 1 and 2 (Golden Retriever) (Autosomal recessive for both forms (ICH1 and ICH2))

Autosomal recessive congenital ichthyosis of the Golden Retriever, with two molecular forms: ICH1, due to a PNPLA1 mutation, and ICH2, due to a deletion in ABHD5 (α/β-hydrolase domain-containing 5), described in 2022 in North American Golden Retrievers. Both share the ω-O-acylceramide biosynthesis pathway of the ski…

Neuronal Ceroid Lipofuscinosis 5 (NCL5) - Golden Retriever (Autosomal recessive)

Neuronal ceroid lipofuscinoses (NCL) are neurodegenerative lysosomal diseases characterized by the accumulation of ceroid lipofuscin (autofluorescent) in neurons and other tissues. The form described in the Golden Retriever is classified within type 5, related to the CLN5 gene. It produces progressive neurological d…

Frequently asked questions

What does this pack include?

It includes 6 hereditary disease tests: Canine Progressive Retinal Atrophy (prcd-PRA), GR-PRA1 (Golden Retriever), GR-PRA2 (Golden Retriever), Muscular Dystrophy (MD) Golden Retriever…. All are analysed in our laboratory.

What do the results mean?

The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.

How is the sample taken?

Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.