Maine Coon Essential Breeding Pack: Feline Blood Group Genetic Testing, Feline Hypertrophic Cardiomyopathy 1 (HCM1), Feline Spinal Muscular Atrophy (SMA), PK Erythrocytic Pyruvate Kinase Deficiency in Cats

Panel de ADN específico para el maine coon que combina la determinación genética del grupo sanguíneo con el cribado de tres enfermedades hereditarias de la raza: miocardiopatía hipertrófica asociada a MYBPC3 (HCM1), deficiencia de piruvato quinasa (PK) y atrofia muscular espinal (SMA). Cubre los sistemas hematológico, cardíaco y neuromuscular. Se realiza a partir de hisopado bucal o sangre e identifica animales portadores y afectados. Es uno de los paneles preventivos más utilizados en la cría felina.

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Diseases included in this pack

Feline blood group genetic determination (dominant and recessive alleles) (Autosomal, CMAH allelic series A > a^c > b. A dominant over b; a^c dominant over b and recessive to A. A/A, A/b, A/a^c = type A; b/b = type B; a^c/a^c and a^c/b = type AB. Group B queens have anti-A antibodies (neonatal isoerythrolysis).)

This test determines by DNA the alleles of the cat AB blood group system: the A allele (dominant) and the b allele (recessive), which define groups A, b/B and AB. The group determines compatibility in transfusions and, above all, the risk of neonatal isoerythrolysis: a group b queen with anti-A antibodies can destro…

Feline Hypertrophic Cardiomyopathy 1 (HCM1) - Maine Coon, Maine Coon Polydactyl, Munchkin, Pixiebob Longhair, Ragdoll, Scottish Fold and Siberian (Autosomal dominant with incomplete penetrance)

Genetic test for the A31P mutation of the MYBPC3 gene associated with hypertrophic cardiomyopathy (HCM) in the Maine Coon, corresponding to a G>C transversion ('HCM1' variant). HCM thickens the left ventricular wall and impairs diastolic function, with a risk of heart failure, thromboembolism and sudden death. It is…

PK Erythrocytic Pyruvate Kinase Deficiency in Cats (Autosomal recessive.)

Erythrocytic pyruvate kinase (PK) deficiency is an inherited haemolytic anaemia caused by variants in the PKLR gene, which encodes the glycolytic enzyme pyruvate kinase. The defective enzyme shortens the lifespan of the erythrocyte and produces haemolytic anaemia of highly variable onset and severity, from mild comp…

SMA (Feline Spinal Muscular Atrophy) - Highlander, Maine Coon and Maine Coon Polydactyl (Autosomal recessive)

Spinal muscular atrophy (SMA) is a hereditary neurodegenerative disease of the Maine Coon characterized by progressive loss of motor neurons in the spinal cord. Without innervation, muscles atrophy gradually and symmetrically, especially in the limbs and trunk. Affected kittens begin weakness around 3-4 months and d…

Frequently asked questions

What does this pack include?

It includes 4 hereditary disease tests: Feline blood group genetic determination (dominant and recessive alleles), Feline Hypertrophic Cardiomyopathy 1 (HCM1) - Maine Coon, Maine Coon Polydactyl, Munchkin, Pixiebob Longhair, Ragdoll, Scottish Fold and Siberian, PK Erythrocytic Pyruvate Kinase Deficiency in Cats, SMA (Feline Spinal Muscular Atrophy) - Highlander, Maine Coon and Maine Coon Polydactyl. All are analysed in our laboratory.

What do the results mean?

The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.

How is the sample taken?

Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.