Fragility and separation of the dorsal hoof wall in young animals, with loss of substance and lameness on hard ground. The frameshift variant in SERPINB11 causes loss of function. Autosomal recessive inheritance. The test is complementary to the clinical and hoof examination.

Connemara Pony. Frequencies: limited data.

- Longitudinal separation of the dorsal hoof wall
- Brittle hoof with fissures and detachments
- Lameness, especially on hard surfaces
- Predominant involvement of young animals

The dossier records OMIA:001897 and the variant SERPINB11 NC_009151.3:g.83600643_83600644insC (c.504_505insC; p.Thr169HisfsTer3; rs3447216148). No author or year is stated.

- Do not mate carriers with each other
- Genotype breeding animals; healthy carriers may be mated with clear animals
- Hoof follow-up of the offspring of carriers

Differential diagnosis with laminitis, white line disease, nutritional disorders (biotin/zinc) and onychia. Complementary: hoof examination and radiography of the hoof.

1. OMIA:001897 Síndrome de separación de la pared del casco (SERPINB11)