Test Detail

Gait / gait keeper (DMRT3) — gaited breeds

General genetics · Horse

A variant associated with the ability to perform lateral gaits (tölt, paso, running walk) and with the coordination of the gait pattern. It is not a disease, but a locomotion and performance trait: the A allele (gait keeper) allows four-beat gaits, while A/A homozygotes show a more pronounced gait and a worse high-speed trot. The test guides selection according to the discipline.
Inheritance patternDominant (gait keeper allele), with dose-dependent expression.
Gene / MutationDMRT3 g.22391254C>A (c.902C>A; p.Ser301Ter; rs1150690013). OMIA:001715.
PenetranceHigh for the gait phenotype; figures not available.
Sample type0,5-1 ml sangre-EDTA o 20-30 pelos de la crin o la cola
Codewxrs
Turnaround time30 days
Price154,45 €
BreedsAppaloosa, Bashkir curly, Caballo de monte, Islandés, Caballo miniatura, Trotador de sangre fría, Kentucky mountain saddle horse, Mangalarga, Missouri fox trotter, Morgan, Paint horse, Paso fino, Peruano de paso, Quarter horse, Saddlebred, Tennessee walking horse

Incidence

American Trotter, Bhotia Pony, Chakouyi, French Trotter, Icelandic Horse, Kentucky Mountain Saddle, Missouri Fox Trotting, Morgan, Paso Fino, Peruvian Paso, Quarter Horse, Rocky Mountain Horse, Scandinavian Coldblood Trotter, Spiti Pony, Tennessee Walking Horse, Thoroughbred and Zaniskari Pony. Frequencies: limited data.

Clinical signs

- Lateral or alternating gait pattern (tölt, paso, running walk)\n- Ease for four-beat gaits\n- Difficulty with high-speed trot in A/A homozygotes\n- It does not in itself involve pathological clinical signs

History

The dossier includes OMIA:001715 and the DMRT3 variant NC_009166.3:g.22391254C>A (c.902C>A; p.Ser301Ter; rs1150690013). No author or year is recorded.

Breeder management

- It is a performance trait, not a disease: it does not require removing breeding animals\n- Use the genotype to guide mating according to the discipline\n- Avoid selecting A/A if the goal is high-speed trot\n- Inform the buyer or registry of the DMRT3 genotype

Specialist notes

It is not a clinical diagnosis; differentiate from lameness and neuromuscular alterations that modify the gait. Complementary: kinematic assessment of the gait and locomotor examination.

References

1. OMIA:001715 Marcha (DMRT3) del caballo

Add to cart

Price: 154,45 € · Turnaround time: 30 days

Add to cart

← Back to the search