Test Detail

Behaviour - Belgian Shepherd

General · Dog

Genetic test associated with behavioural tendencies in the Belgian Shepherd, in particular the Malinois. It evaluates markers related to activity level and reactivity. It is not a Mendelian disease, but a quantitative trait with a genetic component. It should be used as a complementary tool to training and behavioural assessment, never as the sole selection criterion.
Inheritance patternQuantitative trait with a genetic component; it is not a Mendelian disease. Associations with SLC6A3 and CDH2 have been published, not established as a single marker.
Gene / MutationUnconfirmed candidates. Published: intronic 12-nucleotide poly(A) expansion in SLC6A3 (dopamine transporter, DAT), associated with activity and behaviour in the Malinois (Lit et al., 2013; PMID 24376613), and a possible signal in CDH2 (Cao et al., 2014; PMID 25303325). Not established or independently replicated.
PenetranceNot applicable in a clinical sense: the marker informs about a probabilistic tendency, not a deterministic trait.
Codeqxdd
Turnaround time15 days
Price52,60 €

Incidence

Specific to the Belgian Shepherd, in particular the Malinois. Genotype distribution is not published in a consolidated way; limited data.

Breeder management

- Use the result as complementary information, not as the sole selection criterion
- Always combine with behavioural and working assessment of the animal and its ancestors
- Do not discard animals solely on the basis of their behavioural genotype
- Prioritise balance, socialisation and adequate training over the genetic marker

Specialist notes

The interpretation of the result must be cautious: behavioural traits are multifactorial and influenced by genetics, environment, socialisation and training. The marker does not predict aggression or working suitability deterministically. Complementing with professional behavioural evaluation is advisable.

References

1. Lit L et al. 2013. Differences in behavior and activity associated with a poly(A) expansion in the dopamine transporter in Belgian Malinois. PLoS One. PMID: 24376613
2. Cao X et al. 2014. Balancing selection on CDH2 may be related to the behavioral features of the Belgian Malinois. PLoS One. PMID: 25303325

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