Siamese/Oriental Pack: Genetic Blood Group, Gangliosidosis (GM1), Mucopolysaccharidosis Type 6 (MPS6), Primary Congenital Glaucoma (PCG), Progressive Retinal Atrophy (rdAc-PRA)
94,91 € VAT incl.
Panel de ADN para el siamés y el oriental de pelo corto que combina la determinación genética del grupo sanguíneo con el cribado de cuatro enfermedades hereditarias: gangliosidosis GM1, mucopolisacaridosis tipo VI (MPS6), glaucoma congénito primario (PCG) y atrofia progresiva de retina tipo rdAc. Cubre los sistemas nervioso, esquelético-metabólico y ocular. Se realiza a partir de hisopado bucal o sangre e identifica animales portadores y afectados. Resulta especialmente relevante en razas orientales con una base genética históricamente limitada.
Diseases included in this pack
Gangliosidosis (GM1/GM2) (Autosomal recessive)
GM1 and GM2 gangliosidoses are hereditary lysosomal diseases of the cat in which gangliosides accumulate in the nervous system due to a deficiency of degrading enzymes. GM1 is due to beta-galactosidase deficiency and GM2 to alterations of the hexosaminidase system (including its activator protein). The progressive a…
Mucopolysaccharidosis type VI (MPS6) (Autosomal recessive. Severity depends on the allelic combination: L476P/L476P (severe), L476P/D520N (very mild, with joint degeneration) and D520N/D520N (mild). Heterozygotes are clinically healthy carriers.)
Mucopolysaccharidosis type VI (Maroteaux-Lamy disease) is an inherited lysosomal disease caused by arylsulfatase B deficiency, which prevents the breakdown of glycosaminoglycans (mucopolysaccharides). The accumulation affects bones, the cornea, heart valves and internal organs: affected cats grow poorly, with coarse…
Primary Congenital Glaucoma (PCG) (Autosomal recessive, fully penetrant)
Primary congenital glaucoma is an inherited ocular disease described in the Siamese cat in which abnormal development of the drainage angle prevents the normal outflow of aqueous humour. The result is an increase in intraocular pressure from the first weeks or months of life. It progressively and painfully affects t…
Progressive Retinal Atrophy (rdAc-PRA) (Autosomal recessive)
rdAc progressive retinal atrophy is an inherited ocular disease of the cat that causes gradual and irreversible degeneration of the photoreceptors, first the rods and then the cones. It affects the visual system and progresses to complete blindness. Because the loss is slow, many cats adapt for years, but they fail…
Feline blood group genetic determination (dominant and recessive alleles) (Autosomal, CMAH allelic series A > a^c > b. A dominant over b; a^c dominant over b and recessive to A. A/A, A/b, A/a^c = type A; b/b = type B; a^c/a^c and a^c/b = type AB. Group B queens have anti-A antibodies (neonatal isoerythrolysis).)
This test determines by DNA the alleles of the cat AB blood group system: the A allele (dominant) and the b allele (recessive), which define groups A, b/B and AB. The group determines compatibility in transfusions and, above all, the risk of neonatal isoerythrolysis: a group b queen with anti-A antibodies can destro…
Frequently asked questions
What does this pack include?
It includes 5 hereditary disease tests: Gangliosidosis (GM1/GM2), Mucopolysaccharidosis type VI (MPS6), Primary Congenital Glaucoma (PCG), Progressive Retinal Atrophy (rdAc-PRA)…. All are analysed in our laboratory.
What do the results mean?
The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.
How is the sample taken?
Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.
