Persian Pack: Genetic Blood Group, Alpha-Mannosidosis (AMD), Polycystic Kidney Disease (PKD), Progressive Retinal Atrophy (pd-PRA)

Panel de ADN específico para el persa que combina la determinación genética del grupo sanguíneo con el cribado de tres enfermedades hereditarias de la raza: alfa-manosidosis (AMD), enfermedad renal poliquística (PKD) y atrofia progresiva de retina asociada a AIPL1 (PRA-AIPL1, también denominada amaurosis congénita de Leber felina; en catálogos antiguos figura como pd-PRA). Cubre los sistemas metabólico, renal y ocular respectivamente. Se realiza a partir de hisopado bucal o sangre e identifica animales portadores, afectados y predispuestos. Es esencial en una raza con una larga historia de enfermedades hereditarias.

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Diseases included in this pack

Alpha-Mannosidosis (AMD) (Autosomal recessive)

Alpha-mannosidosis is a hereditary lysosomal storage disease of the Persian cat, caused by a deficiency of the enzyme acid alpha-mannosidase (MAN2B1 gene). The defect prevents the breakdown of oligosaccharides, which accumulate in neurons and other cells, producing progressive neurodegeneration. Affected kittens dev…

Progressive feline retinal atrophy (pd-PRA) (Autosomal recessive)

PRA-AIPL1 is a progressive and irreversible degeneration of photoreceptors described in the Persian cat and related breeds, caused by a truncating variant in the AIPL1 gene. OMIA also calls it feline Leber congenital amaurosis (LCA). The published information and frequencies are limited to Persian and related breeds…

PKD PCR (polycystic kidney disease) (Autosomal dominant)

Hereditary kidney disease characterized by the formation of multiple bilateral renal cysts from an early age. The cysts grow progressively, destroy functional parenchyma and progress to chronic kidney failure in adulthood. It is one of the most prevalent and best-characterized feline genetic diseases. The feline for…

Feline blood group genetic determination (dominant and recessive alleles) (Autosomal, CMAH allelic series A > a^c > b. A dominant over b; a^c dominant over b and recessive to A. A/A, A/b, A/a^c = type A; b/b = type B; a^c/a^c and a^c/b = type AB. Group B queens have anti-A antibodies (neonatal isoerythrolysis).)

This test determines by DNA the alleles of the cat AB blood group system: the A allele (dominant) and the b allele (recessive), which define groups A, b/B and AB. The group determines compatibility in transfusions and, above all, the risk of neonatal isoerythrolysis: a group b queen with anti-A antibodies can destro…

Frequently asked questions

What does this pack include?

It includes 4 hereditary disease tests: Alpha-Mannosidosis (AMD), Progressive feline retinal atrophy (pd-PRA), PKD PCR (polycystic kidney disease), Feline blood group genetic determination (dominant and recessive alleles). All are analysed in our laboratory.

What do the results mean?

The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.

How is the sample taken?

Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.