Fox Terrier Pack: Spinocerebellar Ataxia (SCA), Primary Lens Luxation (PLL), van den Ende-Gupta Syndrome (VDEGS)
146,57 € VAT incl.
Panel genético multienfermedad para el Fox terrier que agrupa tres pruebas moleculares de afecciones hereditarias descritas en la raza: ataxia espinocerebelar (SCA), luxación primaria de lente (PLL) y síndrome de van den Ende-Gupta (VDEGS). Cada condición tiene base molecular y herencia propia. El panel es complementario del examen ocular y neurológico en la selección reproductiva.
Diseases included in this pack
Van den Ende-Gupta Syndrome (VDEGS) (Autosomal recessive (OMIA:002016-9615))
Molecular test for canine Van den Ende-Gupta syndrome (VDEGS), a hereditary skeletal development disease described in the Wire Fox Terrier, with severe mandibular prognathism, severe patellar luxation and other skeletal malformations. It is a canine model of the human disease caused by SCARF2. The test reports clear…
Primary Lens Luxation (PLL) (Autosomal recessive (OMIA:000588-9615; Farias et al. 2010).)
Progressive weakening of the zonules of Zinn that causes displacement of the lens. It is a hereditary, non-inflammatory ocular disease, distinct from luxations secondary to cataract, uveitis, previous glaucoma or trauma. When the lens moves into the anterior chamber it can trigger a painful acute glaucoma and rapid…
Canine Cerebellar Ataxia (Autosomal recessive)
Hereditary cerebellar ataxia of the Russell group of terriers and the Fox terrier, caused by a mutation in KCNJ10 (potassium channel Kir4.1). It presents with progressive ataxia, with or without myokymia (fasciculations and muscle rippling) and with or without seizures, and is therefore also known as spinocerebellar…
Frequently asked questions
What does this pack include?
It includes 3 hereditary disease tests: Van den Ende-Gupta Syndrome (VDEGS), Primary Lens Luxation (PLL), Canine Cerebellar Ataxia. All are analysed in our laboratory.
What do the results mean?
The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.
How is the sample taken?
Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.
