Devon Rex Pack: Genetic Blood Group, Congenital Myasthenic Syndrome (CMS), Hair Length (Short Hair/Long Hair), Sphynx/Devon Rex Coat Variant (SPH/DRX)

Panel de ADN específico para el devon rex que combina la determinación genética del grupo sanguíneo con el cribado del síndrome miasténico congénito (SMC) y dos rasgos estéticos: la longitud del pelo y el pelaje ondulado o sin pelo característico del devon rex y el sphynx. El SMC es una grave enfermedad neuromuscular hereditaria, aunque infrecuente; las variantes de pelo permiten predecir la capa de las camadas. Se realiza a partir de hisopado bucal o sangre. Es una herramienta clave para la planificación sanitaria y morfológica de la raza.

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Diseases included in this pack

Sphynx / Devon Rex Coat Variety (SPH/DRX) (Autosomal recessive (each allele in homozygosity))

Genetic test that detects the two known variants of the KRT71 gene responsible, respectively, for the hairless coat of the Sphynx and the curly coat of the Devon rex. Both are distinct alleles of the same locus and can combine in compound animals with an intermediate phenotype. The test allows carriers to be disting…

Congenital Myasthenic Syndrome (CMS) - Devon Rex and Sphynx (Autosomal recessive (OMIA:000684-9685).)

Molecular test for congenital myasthenic syndrome (CMS) in the Devon Rex and Sphynx cat, a hereditary disease of the neuromuscular junction caused by a deficiency of collagen-associated acetylcholinesterase (COLQ). It produces generalised muscle weakness and exercise intolerance due to defective neuromuscular transm…

Feline blood group genetic determination (dominant and recessive alleles) (Autosomal, CMAH allelic series A > a^c > b. A dominant over b; a^c dominant over b and recessive to A. A/A, A/b, A/a^c = type A; b/b = type B; a^c/a^c and a^c/b = type AB. Group B queens have anti-A antibodies (neonatal isoerythrolysis).)

This test determines by DNA the alleles of the cat AB blood group system: the A allele (dominant) and the b allele (recessive), which define groups A, b/B and AB. The group determines compatibility in transfusions and, above all, the risk of neonatal isoerythrolysis: a group b queen with anti-A antibodies can destro…

Feline hair length (Autosomal recessive. Long hair requires two loss-of-function alleles in FGF5 (homozygosity for one variant or compound heterozygosity for two variants); short hair is dominant. It is not a disease.)

Inherited phenotypic trait that determines the long or semi-long coat of the cat. It is not a disease: it depends on loss-of-function variants in the FGF5 gene, which regulate the hair follicle cycle. Short hair is dominant and long hair recessive, so that a long-haired cat is homozygous for one variant or a compoun…

Frequently asked questions

What does this pack include?

It includes 4 hereditary disease tests: Sphynx / Devon Rex Coat Variety (SPH/DRX), Congenital Myasthenic Syndrome (CMS) - Devon Rex and Sphynx, Feline blood group genetic determination (dominant and recessive alleles), Feline hair length. All are analysed in our laboratory.

What do the results mean?

The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.

How is the sample taken?

Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.