Chihuahua Pack: Progressive Retinal Atrophy (prcd-PRA), crd4-PRA, crd4-MAP9 and Lafora Disease
94,38 € VAT incl.
Panel genético multienfermedad del Chihuahua que reúne cuatro pruebas moleculares de afecciones oculares y neurológicas: atrofia progresiva de retina prcd (prcd-PRA), degeneración retiniana de cono-bastón por RPGRIP1 (históricamente cord1 y registrada en OMIA como cone-rod dystrophy 4, crd4), el modificador oligogénico MAP9 (deleción de ~22 kb que agrava la degeneración por RPGRIP1) y la enfermedad de Lafora (epilepsia mioclónica progresiva). El panel es complementario, no sustitutivo, del examen ocular y del seguimiento neurológico en la selección reproductiva.
Diseases included in this pack
Canine Progressive Retinal Atrophy (prcd-PRA) (Autosomal recessive)
Inherited degeneration of the retinal photoreceptors. It begins by affecting the rods (night blindness, difficulty in low light) and progresses toward total vision loss in the medium to long term. It is the most common form of progressive retinal atrophy in dogs and is painless, so it is usually detected late, when…
crd4-PRA / PRA-MAP9 (Autosomal recessive for the RPGRIP1 variant (cord1/crd4); the MAP9 deletion acts as an oligogenic modifier with an accelerating effect. Incomplete penetrance.)
RPGRIP1-CRD retinal degeneration (historically cord1 and registered in OMIA as cone-rod dystrophy 4, crd4) is a progressive retinal atrophy with onset in the puppy caused by the 44 bp insertion in RPGRIP1. The ~22 kb deletion in MAP9 behaves as an oligogenic modifier: it accelerates and aggravates the degeneration o…
Lafora Disease (Autosomal recessive)
Progressive myoclonic epilepsy with accumulation of polyglucosan bodies (Lafora bodies) in the brain and other tissues. It produces myoclonus, especially triggered by sensory stimuli, which progresses to ataxia, cognitive decline and blindness. It is inherited in an autosomal recessive manner and in the dog is assoc…
Cord1 PRA (crd4-PRA, RPGRIP1) (Autosomal recessive with incomplete penetrance.)
Molecular test for cone-rod dystrophy 1 (Cord1) progressive retinal atrophy, a hereditary retinal degeneration that initially affects the cones and later the rods and leads to progressive blindness. It affects the ocular system (photoreceptors) and forces the animal to adapt to gradual visual loss. The test reports…
Frequently asked questions
What does this pack include?
It includes 4 hereditary disease tests: Canine Progressive Retinal Atrophy (prcd-PRA), crd4-PRA / PRA-MAP9, Lafora Disease, Cord1 PRA (crd4-PRA, RPGRIP1). All are analysed in our laboratory.
What do the results mean?
The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.
How is the sample taken?
Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.
