Bolonka Zwetna Pack: Progressive Retinal Atrophy (cord1-PRA), Progressive Retinal Atrophy (prcd-PRA), D-locus d1 (Dilution), Furnishing
146,57 € VAT incl.
Panel genético de la Bolonka zwetna que combina dos pruebas de atrofia progresiva de retina (PRA) — la forma cord1 (RPGRIP1, distrofia de conos y bastones) y la forma prcd (PRCD, degeneración progresiva de bastones y conos) — con dos pruebas de características del manto: la dilución del color (D-locus d1) y el furnishing (bigote y cejas/pelo facial largo). El panel permite la selección de cría tanto para salud ocular como para color y tipo de manto. La prueba de cord1 se ofrece como marcador de riesgo, sin validación raza-específica publicada en la Bolonka.
Diseases included in this pack
D-locus d1 (dilution) MLPH all breeds (Autosomal recessive (D locus). The diluted coat phenotype requires homozygosity of the recessive allele d (d/d); heterozygotes D/d are not diluted.)
Colour dilution associated with the D locus is caused by variants in the MLPH gene (melanophilin). The recessive allele d gives rise to lightened coats (blue, grey, lilac, etc.) and, in a subset of affected dogs, predisposes to colour dilution alopecia (CDA), a dermatosis with hair loss and folliculitis. The effect…
Canine Progressive Retinal Atrophy (prcd-PRA) (Autosomal recessive)
Inherited degeneration of the retinal photoreceptors. It begins by affecting the rods (night blindness, difficulty in low light) and progresses toward total vision loss in the medium to long term. It is the most common form of progressive retinal atrophy in dogs and is painless, so it is usually detected late, when…
Furnishing / wiry coat (RSPO2) (Autosomal trait with variable expression (not a disease); associated with the RSPO2 variant)
A coat variant associated with 'furnishings' (moustache and eyebrows) and facial wire hair in the dog, caused by a 167 bp insertion in the 3'UTR region of the RSPO2 gene. It is not a disease, but a morphological trait with variable expression. The test reports the genotype for the variant.
Cord1 PRA (crd4-PRA, RPGRIP1) (Autosomal recessive with incomplete penetrance.)
Molecular test for cone-rod dystrophy 1 (Cord1) progressive retinal atrophy, a hereditary retinal degeneration that initially affects the cones and later the rods and leads to progressive blindness. It affects the ocular system (photoreceptors) and forces the animal to adapt to gradual visual loss. The test reports…
Frequently asked questions
What does this pack include?
It includes 4 hereditary disease tests: D-locus d1 (dilution) MLPH all breeds, Canine Progressive Retinal Atrophy (prcd-PRA), Furnishing / wiry coat (RSPO2), Cord1 PRA (crd4-PRA, RPGRIP1). All are analysed in our laboratory.
What do the results mean?
The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.
How is the sample taken?
Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.
