Description
Ocular and periocular surface neoplasia (limbus, third eyelid, eyelids) favoured by UV exposure and depigmentation. The variant in DDB2 (nucleotide excision DNA repair) acts as a risk factor, not as a cause. It presents with an ulcerated mass, blepharospasm, epiphora and keratitis. Genetic testing is complementary to clinical examination and biopsy.




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