French Water Dog Pack: Progressive Retinal Atrophy (prcd-PRA), von Willebrand Disease Type 1 (vWD1), D-Locus d1 (Dilution), K-Locus
146,57 € VAT incl.
Panel multienfermedad y de color dirigido al Perro de agua francés (Barbet) que agrupa la prueba de atrofia progresiva de retina prcd-PRA, la enfermedad de von Willebrand tipo 1 (vWD1) y las pruebas de color D-locus d1 (dilución) y K-locus. El panel informa del estatus libre/portador/afecto para prcd-PRA y vWD1 y del genotipo de color para D y K. La prueba molecular no sustituye al examen ocular ni al seguimiento hematológico. La raza aplicable es el Perro de agua francés (Barbet): la vWD1 por VWF c.7437G>A está documentada en esta raza, mientras que no consta documentación en el Perro de agua irlandés (Irish Water Spaniel).
Diseases included in this pack
D-locus d1 (dilution) MLPH all breeds (Autosomal recessive (D locus). The diluted coat phenotype requires homozygosity of the recessive allele d (d/d); heterozygotes D/d are not diluted.)
Colour dilution associated with the D locus is caused by variants in the MLPH gene (melanophilin). The recessive allele d gives rise to lightened coats (blue, grey, lilac, etc.) and, in a subset of affected dogs, predisposes to colour dilution alopecia (CDA), a dermatosis with hair loss and folliculitis. The effect…
von Willebrand Disease Type 1 (Autosomal dominant with incomplete penetrance (classic Doberman form, VWF c.7437G>A))
Von Willebrand disease (vWD) type 1 is an inherited coagulopathy caused by a quantitative deficiency of von Willebrand factor (vWF), a protein required for platelet adhesion to damaged endothelium. The result is a tendency to excessive bleeding, especially from mucous membranes (gums, nose, bladder, digestive tract)…
Canine Progressive Retinal Atrophy (prcd-PRA) (Autosomal recessive)
Inherited degeneration of the retinal photoreceptors. It begins by affecting the rods (night blindness, difficulty in low light) and progresses toward total vision loss in the medium to long term. It is the most common form of progressive retinal atrophy in dogs and is painless, so it is usually detected late, when…
locus e1, K-locus (e1 recessive; K^B dominant)
Coat colour genetic test that determines the genotype of the Extension locus (E, MC1R gene) for the e1 allele (recessive red) and, depending on the panel, the K locus (Dominant Black, CBD103 gene) in the Poodle. The e1 allele in homozygosity (e1/e1) blocks eumelanin production and gives a red/apricot coat, character…
Frequently asked questions
What does this pack include?
It includes 4 hereditary disease tests: D-locus d1 (dilution) MLPH all breeds, von Willebrand Disease Type 1, Canine Progressive Retinal Atrophy (prcd-PRA), locus e1, K-locus. All are analysed in our laboratory.
What do the results mean?
The report shows the genotype and inheritance pattern of each variant. It is a breeding-decision tool: it guides which crosses to avoid, it does not guarantee the absence of disease.
How is the sample taken?
Buccal swab or 0.5–1 ml EDTA blood. The kit ships free to Spain, the EU and the UK.
